• Hours - Mon - Fri: 9:00 - 16:30

Relevant Publications

The reagents developed and offered by Firebird are supported by the following literature:


Benner, S.A. (2004). Chemistry. Redesigning genetics. Science 306, 625–626.

Benner, S.A., Kim, H.-J., Merritt, K.B., Yang, Z., McLendon, D.C., Hoshika, S., and Hutter, D. (2015). Next-generation DNA in pathogen detection, surveillance, and CLIA-waivable diagnostics. SPIE Digital Library 9490, 94900K-94900K – 6.

Biondi, E., Lane, J.D., Das, D., Dasgupta, S., Piccirilli, J.A., Hoshika, S., Bradley, K.M., Krantz, B.A., and Benner, S.A. (2016). Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Res. 44, 9565–9577, PMCID: PMC5175368.

Bradley, K.M., and Benner, S.A. (2014). OligArch: A software tool to allow artificially expanded genetic information systems (AEGIS) to guide the autonomous self-assembly of long DNA constructs from multiple DNA single strands. Beilstein J Org Chem 10, 1826–1833, PMCID: PMC4142867.

Chen, F., Gaucher, E.A., Leal, N.A., Hutter, D., Havemann, S.A., Govindarajan, S., Ortlund, E.A., and Benner, S.A. (2010). Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection. Proc. Natl. Acad. Sci. U.S.A. 107, 1948–1953, PMCID: PMC2804741.

Glushakova, L.G., Bradley, A., Bradley, K.M., Alto, B.W., Hoshika, S., Hutter, D., Sharma, N., Yang, Z., Kim, M.-J., and Benner, S.A. (2015a). High-throughput multiplexed xMAP Luminex array panel for detection of twenty two medically important mosquito-borne arboviruses based on innovations in synthetic biology. J. Virol. Methods 214, 60–74, PMCID: PMC4485418.

Glushakova, L.G., Sharma, N., Hoshika, S., Bradley, A.C., Bradley, K.M., Yang, Z., and Benner, S.A. (2015b). Detecting respiratory viral RNA using expanded genetic alphabets and self-avoiding DNA. Anal. Biochem. 489, 62–72, PMCID: PMC4733849.

Hoshika, S., Chen, F., Leal, N.A., and Benner, S.A. (2010). Artificial genetic systems: self-avoiding DNA in PCR and multiplexed PCR. Angew. Chem. Int. Ed. Engl. 49, 5554–5557, PMCID: PMC6027612.

Hoshika, S., Leal, N.A., Kim, M.-J., Kim, M.-S., Karalkar, N.B., Kim, H.-J., Bates, A.M., Watkins, N.E., SantaLucia, H.A., Meyer, A.J., et al. (2019). Hachimoji DNA and RNA: A genetic system with eight building blocks. Science 363, 884–887, PMCID: PMC6413494.

Hutter, D., Kim, M.-J., Karalkar, N., Leal, N.A., Chen, F., Guggenheim, E., Visalakshi, V., Olejnik, J., Gordon, S., and Benner, S.A. (2010). Labeled nucleoside triphosphates with reversibly terminating aminoalkoxyl groups. Nucleosides Nucleotides Nucleic Acids 29, 879–895, PMCID: PMC3858015.

Jensen, M.A., and Davis, R.W. (2018). Template-Independent Enzymatic Oligonucleotide Synthesis (TiEOS): Its History, Prospects, and Challenges. Biochemistry 57, 1821–1832.

Karalkar, N.B., and Benner, S.A. (2018). The challenge of synthetic biology. Synthetic Darwinism and the aperiodic crystal structure. Curr Opin Chem Biol 46, 188–195.

Leal, N.A., Sukeda, M., and Benner, S.A. (2006). Dynamic assembly of primers on nucleic acid templates. Nucleic Acids Res. 34, 4702–4710, PMCID: PMC1635275.

Merritt, K.K., Bradley, K.M., Hutter, D., Matsuura, M.F., Rowold, D.J., and Benner, S.A. (2014). Autonomous assembly of synthetic oligonucleotides built from an expanded DNA alphabet. Total synthesis of a gene encoding kanamycin resistance. Beilstein J Org Chem 10, 2348–2360, PMCID: PMC4222377.

Sarac, I., and Hollenstein, M. (2019). Terminal Deoxynucleotidyl Transferase in the Synthesis and Modification of Nucleic Acids. Chembiochem 20, 860–871.

Sefah, K., Yang, Z., Bradley, K.M., Hoshika, S., Jiménez, E., Zhang, L., Zhu, G., Shanker, S., Yu, F., Turek, D., et al. (2014). In vitro selection with artificial expanded genetic information systems. Proc. Natl. Acad. Sci. U.S.A. 111, 1449–1454, PMCID: PMC3910645.

Sharma, N., Hoshika, S., Hutter, D., Bradley, K.M., and Benner, S.A. (2014). Recombinase-based isothermal amplification of nucleic acids with self-avoiding molecular recognition systems (SAMRS). Chembiochem 15, 2268–2274.

Sheng, P., Yang, Z., Kim, Y., Wu, Y., Tan, W., and Benner, S.A. (2008). Design of a novel molecular beacon: modification of the stem with artificially genetic alphabet. Chem. Commun. (Camb.) 5128–5130, PMCID: PMC2763601.

Yang, Z., Hutter, D., Sheng, P., Sismour, A.M., and Benner, S.A. (2006). Artificially expanded genetic information system: a new base pair with an alternative hydrogen bonding pattern. Nucleic Acids Res. 34, 6095–6101, PMCID: PMC1635279.

Yang, Z., Sismour